Hemophilia Essay -- essays research papers fc

bleeders disease is the oldest know hereditary expel disorder. There are two types of bleeders disease, A and B (Christmas Disease). Low levels or complete absence of a logical argument protein requirement for clotting causes both. Patients with hemophilia A lack the blood clotting protein, work out VIII, and those with hemophilia B lack agent IX. A person with mischievous hemophilia has less than 1% of the typical total of a clotting element out - either Factor VIII (8) or Factor IX (9). People without hemophilia accept got between 50-150% of the normal level of factor VIII or IX. There are about 20,000 hemophilia patients in the United States. Each year, about 400 babies are innate(p) with this disorder. well-nigh 85% have hemophilia A and the remainder has hemophilia B. The gruesomeness of hemophilia is related to the amount of the clotting factor in the blood. well-nigh 70% of hemophilia patients have less than one percent of the normal amount and, thus, have p rankish hemophilia. A small increase in the blood level of the clotting factor, up to five percent of normal, results in mild hemophilia with rare bleeding except after injuries or surgery.This is not a problem when a person with hemophilia has a simple cut or scrape. He doesnt bleed some(prenominal) faster than the average person. He potbelly hold pressure on the cut and platelets in the blood will stop the bleeding.The problem for citizenry with hemophilia is bleeding privileged the body, especially bleeding into commons like the knees, elbows, and ankles. When bleeding happens inside the joint, it becomes very swollen and painful. Repeated bleeding into a joint can cause a type of crippling arthritis. Bleeding inside other parts of the body, such as the brain, throat, and abdomen can be life-threatening. A person with mild hemophilia may only have problems with bleeding when he has surgery, major dental work, or a severe injury. A person with moderate hemophilia will have th ose problems incontrovertible bleeding problems with more minor injuries such as a seriously bump to the knee. A person with severe hemophilia can have what are called spontaneous bleeds - bleeding that starts inside the body for no cognise reason.Hemophilia is classified as mild, moderate or severe, depending on the amount of clotting factor a person has in his body. Severe hemophilia is actually the most common stratum. People with hemophilia are born with the disorder and have it all of their lives. You cant ca... ...ed HIV.Factor VIII gene is characterized and cloned. 1985Viral-inactivated factor concentrates become available.ELISA and Western Blot Test are developed to test antibodies for HIV.1989Hepatitis C virus, previously called non-A, non-B, is identified.1991Testing for hepatitis C is introduced.1992First recombinant factor VIII products become available.1995First case of variant Creutzfeldt-Jakob disease, the human form of Mad Cow disease, is identified in the U.K. 1997First recombinant factor IX products become available.1998Gene therapy trials on humans begin.Effective treatment for hemophilia is available, but as yet there is no cure. Bleeding can be treated with an injection of clotting factor that is made from blood or biotechnological ingredients called recombinants. Bleeding stops when enough clotting factor reaches the bear on area. Works CitedI.Principles Of Genetics 7th Edition, Robert H. Tamarin. 2002II.World Federation of Hemophilia. www.wfh.orgIII.Hemophilia of Georgia. www.hog.orgIV.Hemophilia Village. Hemophiliavillage.com